Claim: CDC data indicate that 146 neurological and psychiatric safety signals have been reported for COVID‑19 vaccines.
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The apparent source is a preprint by Thorp et al. titled “Association between COVID-19 Vaccination and Neuropsychiatric Conditions” posted on Preprints.org in April 202512. It is explicitly labeled “NOT PEER-REVIEWED” and lists authors including Peter McCullough, who has a documented history of promoting vaccine misinformation.
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That preprint analyzed VAERS data and reported that proportional-reporting-ratio thresholds were breached for 86 adverse events: 47 related to cognitive impairment, 28 to general psychiatric illness, and 11 to suicide/homicide34. It did not report 146 signals.
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Nicolas Hulscher, an epidemiologist affiliated with the McCullough Foundation who wrote about the study, stated it identified “86 serious neuropsychiatric safety signals”5. The figure of 146 appears in social media posts that misrepresented or inflated the preprint’s findings67.
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VAERS is a passive reporting system co-managed by CDC and FDA; raw VAERS reports do not prove causation and are not equivalent to official CDC safety-signal findings8. Official CDC monitoring relies on active surveillance systems (e.g., Vaccine Safety Datalink) and has confirmed only a small number of neurological signals, such as Guillain-Barré syndrome with the Johnson & Johnson vaccine98.
Overall validity: 0%
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